PRECISION BIOSCIENCES INC — Director's Dealing 2026

Jan 22, 2026

SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: PRECISION BIOSCIENCES INC (DTIL)
CIK: 0001357874
Period of Report: 2026-01-20

Reporting Person: Amoroso Michael (Director, President and CEO)

Non-Derivative Transactions

Date	Security	Code	Shares	Price	A/D	Holdings After	Ownership
2026-01-20	Common Stock	M	8888	—	Acquired	124463	Direct
2026-01-20	Common Stock	M	37069	—	Acquired	161532	Direct
2026-01-20	Common Stock	M	69421	—	Acquired	230953	Direct
2026-01-22	Common Stock	S	34799	$4.17	Disposed	196154	Direct

Derivative Transactions

Date	Security	Exercise Price	Code	Shares	A/D	Expiration	Underlying	Ownership
2026-01-20	Restricted Stock Units	$	M	8888	Disposed		Common Stock (8888)	Direct
2026-01-20	Restricted Stock Units	$	M	37069	Disposed		Common Stock (37069)	Direct
2026-01-20	Restricted Stock Units	$	M	69421	Disposed		Common Stock (69421)	Direct

Footnotes

F1: Represents the vesting of Restricted Stock Units ("RSUs") on January 20, 2026.

F2: Each RSU represents a contingent right to receive one share of the Issuer's Common Stock.

F3: The sales were effected pursuant to a Rule 10b5-1 plan adopted on August 2, 2024. The transaction was a sell-to-cover, with shares only sold to cover tax withholding obligations in connection with the vesting and settlement of RSUs. The Reporting Person did not sell or otherwise dispose of shares reported on this Form 4 for any reason other than to cover required taxes and fees.

F4: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $3.97 to $4.30. The Reporting Person undertakes to provide the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote

F5: On January 20, 2023 the Reporting Person was granted RSUs, which vested in three substantially equal annual installments beginning on January 20, 2024, subject to the Reporting Person's continued service to the Issuer through the applicable vesting dates.

F6: On April 18, 2024 the Reporting Person was granted RSUs, which vest in three substantially equal annual installments beginning on January 20, 2025, subject to the Reporting Person's continued service to the Issuer through the applicable vesting dates.

F7: On August 22, 2024 the Reporting Person was granted RSUs, which vest in three substantially equal annual installments beginning on January 20, 2025, subject to the Reporting Person's continued service to the Issuer through the applicable vesting dates.