PRECISION BIOSCIENCES INC — Director's Dealing 2026

Jan 22, 2026

SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: PRECISION BIOSCIENCES INC (DTIL)
CIK: 0001357874
Period of Report: 2026-01-20

Reporting Person: SMITH J. JEFFERSON (Chief Research Officer)

Non-Derivative Transactions

Date	Security	Code	Shares	Price	A/D	Holdings After	Ownership
2026-01-20	Common Stock	M	2500	—	Acquired	93718	Direct
2026-01-20	Common Stock	M	10447	—	Acquired	104165	Direct
2026-01-21	Common Stock	M	16219	—	Acquired	120384	Direct
2026-01-21	Common Stock	S	10200	$4.03	Disposed	110184	Direct

Derivative Transactions

Date	Security	Exercise Price	Code	Shares	A/D	Expiration	Underlying	Ownership
2026-01-20	Restricted Stock Units	$	M	2500	Disposed		Common Stock (2500)	Direct
2026-01-20	Restricted Stock Units	$	M	10447	Disposed		Common Stock (10447)	Direct
2026-01-20	Restricted Stock Units	$	M	16219	Disposed		Common Stock (16219)	Direct

Holdings (Non-Derivative)

Security	Shares	Ownership
Common Stock	7931	Indirect

Footnotes

F1: Represents the vesting of Restricted Stock Units ("RSUs") on January 20, 2026.

F2: Each RSU represents a contingent right to receive one share of the Issuer's Common Stock.

F3: Includes 3,413 shares acquired under the Issuer's 2019 Employee Stock Purchase Plan at a weighted average price per share of $5.74

F4: The sales were effected pursuant to a Rule 10b5-1 plan adopted on April 25, 2024. The transaction was a sell-to-cover, with shares only sold to cover tax withholding obligations in connection with the vesting and settlement of RSUs. The Reporting Person did not sell or otherwise dispose of shares reported on this Form 4 for any reason other than to cover required taxes and fees.

F5: On January 20, 2023 the Reporting Person was granted RSUs, which vested in three substantially equal annual installments beginning on January 20, 2024, subject to the Reporting Person's continued service to the Issuer through the applicable vesting dates.

F6: On April 18, 2024 the Reporting Person was granted RSUs, which vest in three substantially equal annual installments beginning on January 20, 2025, subject to the Reporting Person's continued service to the Issuer through the applicable vesting dates.

F7: On August 22, 2024 the Reporting Person was granted RSUs, which vest in three substantially equal annual installments beginning on January 20, 2025, subject to the Reporting Person's continued service to the Issuer through the applicable vesting dates.