Pluri Inc. — Director's Dealing 2025

Oct 16, 2025

FORM 4

Check this box if no longer subject to

UNITED STATES SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL	OWNERSHIP

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Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.

Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940

1. Name and Address of Reporting Person* YANAY YAKY			Issuer Name and Ticker or Trading Symbol Pluri Inc. [ PLUR ]	Relationship of Reporting Person(s) to Issuer (Check all applicable) X Director 10% Owner
(Last) (First) (Middle) C/O PLURI INC. MATAM ADVANCED TECH PARK BUILDING 5		,	3. Date of Earliest Transaction (Month/Day/Year) 10/15/2025	X	Officer (give title below) Chief Executive O	Other (specify below)
(Street) HAIFA (City)	L3 (State)	3508409 (Zip)	4. If Amendment, Date of Original Filed (Month/Day/Year)	6. Individu	ual or Joint/Group Filing (Check Ap Form filed by One Reporting Per Form filed by More than One Re	rson

Table I – Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any	3. Transa Code (Ins		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			Beneficially Owned Following Reported	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial
		(Month/Day/Year)	Code	V	Amount	(A) or (D) Price		Transaction(s) (Instr. 3 and 4)		Ownership (Instr. 4)
Common Stock	10/15/2025 (1)		A		39,050 (1)	A	\$0	491,170	D
Common Stock								836	I	By Yaacov Yanay Management Ltd.

Table II – Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	Conversion	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transa Code (Ins				6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	Beneficially Owned Following Reported	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares		Transaction(s) (Instr. 4)
Stock Option	\$5	10/15/2025		A		39,050		10/15/2025 (2)	10/15/2028	Common Stock	39,050	\$0	39,050	D

Explanation of Responses:

• 1. Represents restricted stock units that are fully vested.
• 1. The stock options are fully vested.

/s/ Yaky Yanay 10/16/2025

** Signature of Reporting Person Date

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.

• * If the form is filed by more than one reporting person, see Instruction 4(b)(v).
• ** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).

Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.

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