Oxurion NV — Major Shareholding Notification 2025

Jun 18, 2025

Oxurion Receives Transparency Notification from Atlas Special Opportunities II LLC

Leuven, BELGIUM – June 18, 2025 – 06:00 PM CET - Oxurion NV (Euronext Brussels: OXUR), a biopharmaceutical company headquartered in Leuven, today announced that, pursuant to Belgian Transparency legislation¹ it has received a transparency notification as follows:

Oxurion received a transparency notification on June 16, 2025, from Atlas Special Opportunities II, LLC indicating that as of June 10, 2025, it held 1,548,410 shares of the then outstanding 8,496,303 shares, and therefore crossed under the threshold (20%) by virtue of the selling of voting securities.

About Oxurion

Oxurion NV (Euronext Brussels: OXUR) is a biopharmaceutical group in transition, combining therapeutic innovation with technologies applied to clinical research. Through its rapidly expanding technology division, Oxurion is building integrated expertise around clinical data, with the ambition to accelerate, secure, and transform the processes involved in developing new treatments. The Group's headquarters are based in Leuven, Belgium. More information is available at www.oxurion.com.

Important information about forward-looking statements

Certain statements in this press release may be considered "forward-looking". Such forward-looking statements are based on current expectations, and, accordingly, entail and are influenced by various risks and uncertainties. The Company therefore cannot provide any assurance that such forward-looking statements will materialize and does not assume any obligation to update or revise any forward-looking statement, whether as a result of new information, future events, or any other reason. Additional information concerning risks and uncertainties affecting the business and other factors that could cause actual results to differ materially from any forwardlooking statement is contained in the Company's Annual Report. This press release does not constitute an offer or invitation for the sale or purchase of securities or assets of Oxurion in any jurisdiction. No securities of Oxurion may be offered or sold within the United States without registration under the U.S. Securities Act of 1933, as amended, or in compliance with an exemption therefrom, and in accordance with any applicable U.S. state securities laws.

For further information please contact:

Oxurion NV Pascal Ghoson Chief Executive Officer Pascal.ghoson@oxurion.com

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1. Article 14, first paragraph, of the Law of 2 May 2007 on disclosure of major holdings.

ANNEX 1

FSMA	FINANCIAL SERVICES AND MARKETS AUTHORITY		Form TR-1 BE PART I	Transparency notification
1) Status of the notification
	Final
2) Issuer
Identification number 0881-620-924	Name OXURION
3) Reason for the notification
	Acquisition or disposal of voting securities or voting rights
4) Notification by
	A person that notifies alone
5) Persons subject to the notification requirement
	Name				Address (for legal entitles)
	Atlas Special Opportunities II LLC			2500 Westchester Avenue, Suite 401, Purchase, NY 10577
6) Persons that dispose of voting rights (only to be filled in it art. 7 of the Law applies)
	Name				Address (for legal entitles)
	Please continue entering the information in part if concerning the persons referred to In Sections 5 and 6			Part II
7) Date on which the threshold is crossed
			10/06/2025 (DD/MM/YYYYY)
8) Threshold that is crossed (In %)
		20
	r the holding has fallen below the lowest threshold, you have the option of not entering any numbers in Section 10
9) Denominator
		8,496,303
	Please enter the denominator before filling in the data
10) Notified details
A) Voting rights	Previous notification			After the transaction
	# of voting rights		# of voting rights	Not linked to the		% of voting rights Not linked to the

B) Equivalent financial Instruments	After the transaction
Holders of equivalent financial Instruments	Type of financial Instrument	Expiration data	Exercise period or date	# of voting rights that may be acquired if the Instrument Is exercised	% of voting rights	Settlement
							+
	TOTAL			0	0.00%
10	The torals will be updated once you have clicked on «CALCULATE>

TOTAL (A & B)			# of voting rights % of voting rights
	CALCULATE	1,548,410	18.22%

11) Full chain of controlled undertakings through which the holding is effectively held, it applicable

12) In case of proxy voting for only one GM

Holder	will cease to hold / will hold again	voting rights as of

13) Additional information

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Done at New York
On	12/06/2025 (DD/MM/YYYYY)
Name & capacity Patrick Vance, Proxyhoider	Patrick Vance Signature CONSULTIONAL

For security reasons, the unsigned form in xlsx format should
be transmitted to trp.fin@fsms.be. You can do this manually
OR if you have MS Outlook at your disposal via th

In addition, a signed copy in PDE format should also be transmitted.