OXFORD CANNABINOID TECHNOLOGIES HOLDINGS PLC — Proxy Solicitation & Information Statement 2021

Oct 27, 2021

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Computershare Investor Services PLC The Pavilions, Bridgwater Road Bristol, BS99 6ZZ Tel: 0370 703 0342

IMPORTANT NOTICE

If you are in any doubt as to what action to take please consult an appropriate independent advisor

Shareholder Reference Number (SRN)

Help reduce the environmental impact of your communications

Dear shareholder

As a shareholder, you can help reduce the environmental impact of your communications by choosing to receive your shareholder communications in electronic form.

The Companies Act allows the default option for receiving and accessing shareholder communications (including your annual report) to be via a company's website. You now have the choice of receiving an email when your annual report and other shareholder communications become available or continuing to receive a printed copy.

Please select one of the options opposite

If you do not indicate your preference to us by 26 November 2021 shareholder communications will be supplied to you by means of the website and information on accessing your shareholder communications online will be posted to you at the time of the mailing.

If you have any questions about this letter please refer to the back of this letter for more details.

Yours sincerely

Clarissa Sowemimo Coker Chief Operating Officer and General Counsel

What are your options?

Option 1 Elect for ecommunications

www.investorcentre.co.uk/ecomms

Alternatively provide us with your e-mail address on the form overleaf.

You will receive an email notification when your shareholder communications become available online.

Option 2

To continue receiving printed copies of your shareholder communications on the reverse form.

Like the sound of ecommunications?

You can manage your shareholding online. Investor Centre is our free self-service website. Register at www.investorcentre.co.uk and manage your shareholding with ease!

Please make your selection

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Option 1 Receive email notifications when your shareholder communications are available online Please submit your email address and SRN by visiting our Investor Centre website:

www.investorcentre.co.uk/ecomms

SRN: !YOUR SRN IS IMPORTANT, PLEASE KEEP IT IN A SAFE PLACE.

By providing your email address and SRN above you will no longer receive paper copies of annual reports or other communications that are available electronically. Instead you will receive emails advising you when and how to access documents online.

Alternatively enter your email address below and send this form back in the enclosed reply paid envelope.

How to complete this form

Please use a black pen. Print in CAPITAL letters inside the boxes as shown in this example.

Option 2 Continue receiving a printed copy of all your communications.

To continue to receive a printed copy of the annual report and other shareholder communications please cross this box and send this letter back to us in the enclosed reply paid envelope.