Nuvalent, Inc. — Director's Dealing 2025

Oct 17, 2025

SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: Nuvalent, Inc. (NUVL)
CIK: 0001861560
Period of Report: 2025-10-15

Reporting Person: Balcom Alexandra (N/A)

Non-Derivative Transactions

Date	Security	Code	Shares	Price	A/D	Holdings After	Ownership
2025-10-15	Class A Common Stock	M	1683	$18.93	Acquired	63417	Direct
2025-10-15	Class A Common Stock	S	1683	$85.57	Disposed	61734	Direct

Derivative Transactions

Date	Security	Exercise Price	Code	Shares	A/D	Expiration	Underlying	Ownership
2025-10-15	Stock Option (Right to Buy)	$18.93	M	1683	Disposed	2032-01-04	Class A Common Stock (1683)	Direct

Footnotes

F1: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on December 12, 2024.

F2: The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $85.00 to $85.69, inclusive. The reporting person undertakes to
provide to the staff of the Securities and Exchange Commission, Nuvalent, Inc. or any security holder of Nuvalent, Inc., upon request, full information regarding the number of shares sold
at each separate price.

F3: The shares underlying this option vest as follows: 25% of the shares vested on January 4, 2023, and the remainder have vested or shall vest over the three years thereafter in equal monthly installments, subject to continued service to Nuvalent, Inc. through the applicable vesting date.