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MORGAN STANLEY Capital/Financing Update 2010

Sep 30, 2010

29766_prs_2010-09-30_ca23ce5e-58c4-4e4a-be62-9ba70a6fad89.zip

Capital/Financing Update

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CALCULATION OF REGISTRATION FEE — Title of Each Class of Securities Offered Maximum Aggregate Offering Price Amount of Registration Fee
Index LeAding StockmarkEt Return Securities due 2011 $3,650,000 $260.25

September 2010 Pricing Supplement No. 537 Registration Statement No. 333-156423 Dated September 28, 2010 Filed pursuant to Rule 424(b)(2)

S T R U C T U R E D I N V E S T M E N T S

Opportunities in International Equities

Index LASERS SM Based on the Value of the Dow Jones EURO STOXX 50 ® Index due October 6, 2011

Index LeAding StockmarkEt Return Securities

The Index LASERS, which we refer to as the LASERS, are senior unsecured obligations of Morgan Stanley, will pay no interest, do not guarantee any return of principal at maturity and have the terms described in the prospectus supplement for LASERS and the prospectus, as supplemented or modified by this pricing supplement. At maturity, an investor will receive for each stated principal amount of LASERS that the investor holds an amount in cash that may be greater than, equal to or less than the stated principal amount based on (i) the index closing value on the valuation date and (ii) whether the closing value of the underlying index has declined to or below the downside threshold value on any index business day during the period from but excluding the pricing date to and including the valuation date. The LASERS are senior unsecured notes issued as part of Morgan Stanley’s Series F Global Medium-Term Notes program. All payments on the LASERS are subject to the credit risk of Morgan Stanley.

FINAL TERMS — Issuer: Morgan Stanley
Aggregate principal amount: $3,650,000
Stated principal amount: $10 per LASERS
Issue price: $10 per LASERS
Pricing date: September 28, 2010
Original issue date: September 30, 2010 (2 business days after the pricing date)
Maturity date: October 6, 2011
Underlying index: Dow Jones EURO STOXX 50 ® Index
Payment at maturity: $10 + index return amount; subject to the maximum payment at maturity. This payment may be greater than, equal to or less than the stated principal amount.
Index return amount: If the index closing value is greater than the downside threshold value on each index business day during the period from but excluding the pricing date to and including the valuation date, the index return amount will equal: $10 x [the greater of (i) the index percent change and (ii) the fixed percentage] If the index closing value is less than or equal to the downside threshold value on any index business day during the period from but excluding the pricing date to and including the valuation date, the index return amount will equal: $10 x the index percent change In this scenario, the payment at maturity may be less, and potentially significantly less, than the stated principal amount and could be zero. There is no minimum payment at maturity on the LASERS.
Fixed percentage: 10%
Maximum payment at maturity: $12.00 per LASERS
Index percent change: (final index value – initial index value) / initial index value
Initial index value: 2,774.62, which is the index closing value on the pricing date.
Final index value: The index closing value on the valuation date
Downside threshold value: 2,080.965, which is 75% of the initial index value.
Valuation date: October 3, 2011, subject to adjustment for non-index business days and certain market disruption events
CUSIP: 61759G398
ISIN: US61759G3983
Listing: The LASERS will not be listed on any securities exchange.
Agent: Morgan Stanley & Co. Incorporated (“MS & Co.”), a wholly-owned subsidiary of Morgan Stanley. See “Supplemental information concerning plan of distribution; conflicts of interest.”
Commissions and Issue Price: Price to Public Agent’s Commissions (1) Proceeds to Issuer
Per LASERS $10 $0.11425 $9.88575
Total $3,650,000 $41,701.25 $3,608,298.75

(1) Selected dealers, including Morgan Stanley Smith Barney LLC (an affiliate of the Agent), and their financial advisors will collectively receive from the Agent, MS & Co., a fixed sales commission of $0.11425 for each LASERS they sell. See “Supplemental information concerning plan of distribution; conflicts of interest” on page 5. For additional information, see “Plan of Distribution (Conflicts of Interest)” in the accompanying prospectus supplement for LASERS.

The LASERS involve risks not associated with an investment in ordinary debt securities. See “Risk Factors” beginning on page 10.

The Securities and Exchange Commission and state securities regulators have not approved or disapproved these securities, or determined if this pricing supplement or the accompanying prospectus supplement and prospectus is truthful or complete. Any representation to the contrary is a criminal offense.

You should read this document together with the related prospectus supplement and prospectus, each of which can be accessed via the hyperlinks below.

EFPlaceholder Prospectus Supplement for LASERS dated February 23, 2010

EFPlaceholder Prospectus dated December 23, 2008

The LASERS are not bank deposits and are not insured or guaranteed by the Federal Deposit Insurance Corporation or any other governmental agency, nor are they obligations of, or guaranteed by, a bank.

FWP: MSPRB0210002

Index LASERS SM Based on the Value of the Dow Jones EURO STOXX 50 ® Index due October 6, 2011

Index LeAding StockmarkEt Return Securities

Fact Sheet

The LASERS are senior unsecured obligations of Morgan Stanley, will pay no interest, do not guarantee any return of principal at maturity and have the terms described in the prospectus supplement for LASERS and the prospectus, as supplemented or modified by this pricing supplement. At maturity, an investor will receive for each stated principal amount of LASERS that the investor holds an amount in cash that may be greater than, equal to or less than the stated principal amount based on (i) the index closing value on the valuation date and (ii) whether the closing value of the underlying index has declined to or below the downside threshold value on any index business day during the period from but excluding the pricing date to and including the valuation date. The LASERS are senior unsecured notes issued as part of Morgan Stanley’s Series F Global Medium-Term Notes program. All payments on the LASERS are subject to the credit risk of Morgan Stanley. “Index LASERS SM ” is a registered service mark of Citigroup Global Markets Inc. Used under license.

Key Dates — Pricing date: Original issue date (settlement date): Maturity date:
September 28, 2010 September 30, 2010 (2 business days after the pricing date) October 6, 2011 (subject to postponement as described below)
Key Terms
Issuer: Morgan Stanley
Underlying index: Dow Jones EURO STOXX 50 ® Index
Underlying index publisher: Dow Jones & Company, Inc.
Aggregate principal amount: $3,650,000
Issue price: $10 per LASERS
Stated principal amount: $10 per LASERS
Denominations: $10 per LASERS and integral multiples thereof
Interest: None
Payment at maturity: $10 + index return amount; subject to the maximum payment at maturity. This payment may be greater than, equal to or less than the stated principal amount.
Index return amount: If the index closing value is greater than the downside threshold value on each index business day during the period from but excluding the pricing date to and including the valuation date, the index return amount will be positive and will equal: $10 x [the greater of (x) the index percent change and (y) the fixed percentage] If the index closing value is less than or equal to the downside threshold value on any index business day during the period from but excluding the pricing date to and including the valuation date, the index return amount will equal: $10 x the index percent change In this scenario, the payment at maturity may be less, and potentially significantly less, than the stated principal amount and could be zero. There is no minimum payment at maturity on the LASERS.
Fixed percentage: 10%
Maximum payment at maturity: $12.00 per LASERS
Index percent change: (final index value – initial index value) / initial index value
Initial index value: 2,774.62, which is the index closing value on the pricing date as published by the underlying index publisher.
Final index value: The index closing value on the determination date as published by the underlying index publisher
Downside threshold value: 2,080.965, which is 75% of the initial index value.
Valuation date: October 3, 2011, subject to adjustment for non-index business days and certain market disruption events
Postponement of maturity date: If the scheduled valuation date is not an index business day or if a market disruption event occurs on that day so that the valuation date is postponed and falls less than two business days prior to the scheduled maturity date, the maturity date will be postponed to the second business day following the valuation date as postponed.
Risk factors: Please see “Risk Factors” beginning on page 10.

September 2010 Page 2

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Index LeAding StockmarkEt Return Securities

General Information
Listing: The LASERS will not be listed on any securities exchange.
CUSIP: 61759G398
ISIN: US61759G3983
Minimum ticketing size: 100 LASERS
Tax considerations: Although the issuer believes that, under current law, the LASERS should be treated as a single financial contract that is an “open transaction” for U.S. federal income tax purposes, there is uncertainty regarding the U.S. federal income tax consequences of an investment in the LASERS.
Assuming this treatment of the LASERS is respected and subject to the discussion in “United States Federal Taxation” in the accompanying prospectus supplement for LASERS, the following U.S. federal income tax consequences should result based on current law:
§ A U.S. Holder should not be required to recognize taxable income over the term of the LASERS prior to maturity, other than pursuant to a sale or exchange.
§ Upon sale, exchange or settlement of the LASERS at maturity, a U.S. Holder should recognize gain or loss equal to the difference between the amount realized and the U.S. Holder’s tax basis in the LASERS. Such gain or loss should be long-term capital gain or loss if the investor has held the LASERS for more than one year.
On December 7, 2007, the Treasury Department and the Internal Revenue Service (the “IRS”) released a notice requesting comments on the U.S. federal income tax treatment of “prepaid forward contracts” and similar instruments, such as the LASERS . The notice focuses in particular on whether to require holders of these instruments to accrue income over the term of their investment. It also asks for comments on a number of related topics, including the character of income or loss with respect to these instruments; whether short-term instruments should be subject to any such accrual regime; the relevance of factors such as the exchange-traded status of the instruments and the nature of the underlying property to which the instruments are linked; the degree, if any, to which income (including any mandated accruals) realized by non-U.S. investors should be subject to withholding tax; and whether these instruments are or should be subject to the “constructive ownership” regime, which very generally can operate to recharacterize certain long-term capital gain as ordinary income that is subject to an interest charge. While the notice requests comments on appropriate transition rules and effective dates, any Treasury regulations or other guidance promulgated after consideration of these issues could materially and adversely affect the tax consequences of an investment in the LASERS , possibly with retroactive effect. Both U.S. and non-U.S. investors considering an investment in the LASERS should read the discussion under “Risk Factors” in this document and the discussion under “United States Federal Taxation” in the accompanying prospectus supplement for LASERS and consult their tax advisers regarding all aspects of the U.S. federal income tax consequences of an investment in the LASERS, including possible alternative treatments, the issues presented by the aforementioned notice and any tax consequences arising under the laws of any state, local or foreign taxing jurisdiction.
Trustee: The Bank of New York Mellon (as successor trustee to JPMorgan Chase Bank, N.A.)
Calculation agent: MS & Co.
Use of proceeds and hedging: The net proceeds we receive from the sale of the LASERS will be used for general corporate purposes and, in part, in connection with hedging our obligations under the LASERS through one or more of our subsidiaries . On or prior to the pricing date, we, through our subsidiaries or others, hedged our anticipated exposure in connection with the LASERS by taking positions in the stocks constituting the underlying index and in futures or options contracts listed on major securities markets on the underlying index and its component stocks. Such purchase activity could have increased the closing value of the underlying index on the pricing date, and accordingly, could have increased the index closing value above which the underlying index must remain so that the downside threshold value is not reached and, if the downside threshold value is reached, could have increased the index closing value at which the underlying index must be on the valuation date before you would receive at maturity a payment that exceeds the stated principal amount of the LASERS. For further information on our use of proceeds and hedging, see “Use of Proceeds and Hedging” in the accompanying prospectus supplement for

September 2010 Page 3

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Index LeAding StockmarkEt Return Securities

LASERS.
Benefit plan investor considerations: Each fiduciary of a pension, profit-sharing or other employee benefit plan subject to the Employee Retirement Income Security Act of 1974, as amended (“ERISA”) (a “Plan”), should consider the fiduciary standards of ERISA in the context of the Plan’s particular circumstances before authorizing an investment in the LASERS. Accordingly, among other factors, the fiduciary should consider whether the investment would satisfy the prudence and diversification requirements of ERISA and would be consistent with the documents and instruments governing the Plan. In addition, we and certain of our subsidiaries and affiliates, including MS & Co., may each be considered a “party in interest” within the meaning of ERISA, or a “disqualified person” within the meaning of the Internal Revenue Code of 1986, as amended (the “Code”), with respect to many Plans, as well as many individual retirement accounts and Keogh plans (also “Plans”). ERISA Section 406 and Code Section 4975 generally prohibit transactions between Plans and parties in interest or disqualified persons. Prohibited transactions within the meaning of ERISA or the Code would likely arise, for example, if the LASERS are acquired by or with the assets of a Plan with respect to which MS & Co. or any of its affiliates is a service provider or other party in interest, unless the LASERS are acquired pursuant to an exemption from the “prohibited transaction” rules. A violation of these “prohibited transaction” rules could result in an excise tax or other liabilities under ERISA and/or Section 4975 of the Code for those persons, unless exemptive relief is available under an applicable statutory or administrative exemption. The U.S. Department of Labor has issued five prohibited transaction class exemptions (“PTCEs”) that may provide exemptive relief for direct or indirect prohibited transactions resulting from the purchase or holding of the LASERS. Those class exemptions are PTCE 96-23 (for certain transactions determined by in-house asset managers), PTCE 95-60 (for certain transactions involving insurance company general accounts), PTCE 91-38 (for certain transactions involving bank collective investment funds), PTCE 90-1 (for certain transactions involving insurance company separate accounts) and PTCE 84-14 (for certain transactions determined by independent qualified professional asset managers). In addition, ERISA Section 408(b)(17) and Section 4975(d)(20) of the Code may provide an exemption for the purchase and sale of securities and the related lending transactions, provided that neither the issuer of the securities nor any of its affiliates has or exercises any discretionary authority or control or renders any investment advice with respect to the assets of the Plan involved in the transaction and provided further that the Plan pays no more, and receives no less, than “adequate consideration” in connection with the transaction (the so-called “service provider” exemption). There can be no assurance that any of these class or statutory exemptions will be available with respect to transactions involving the LASERS. Because we may be considered a party in interest with respect to many Plans, the LASERS may not be purchased, held or disposed of by any Plan, any entity whose underlying assets include “plan assets” by reason of any Plan’s investment in the entity (a “Plan Asset Entity”) or any person investing “plan assets” of any Plan, unless such purchase, holding or disposition is eligible for exemptive relief, including relief available under PTCEs 96-23, 95-60, 91-38, 90-1, 84-14 or the service provider exemption or such purchase, holding or disposition is otherwise not prohibited. Any purchaser, including any fiduciary purchasing on behalf of a Plan, transferee or holder of the LASERS will be deemed to have represented, in its corporate and its fiduciary capacity, by its purchase and holding of the LASERS that either (a) it is not a Plan or a Plan Asset Entity and is not purchasing such LASERS on behalf of or with “plan assets” of any Plan or with any assets of a governmental, non-U.S. or church plan that is subject to any federal, state, local or non-U.S. law that is substantially similar to the provisions of Section 406 of ERISA or Section 4975 of the Code (“Similar Law”) or (b) its purchase, holding and disposition are eligible for exemptive relief or such purchase, holding or disposition are not prohibited by ERISA or Section 4975 of the Code or any Similar Law. Due to the complexity of these rules and the penalties that may be imposed upon persons involved in non-exempt prohibited transactions, it is particularly important that fiduciaries or other persons considering purchasing the LASERS on behalf of or with “plan assets” of any Plan consult with their counsel regarding the availability of exemptive relief. Each purchaser and holder of the LASERS has exclusive responsibility for ensuring that its purchase, holding and disposition of the LASERS do not violate the prohibited transaction rules of ERISA or the Code or any Similar Law. The sale of any LASERS to any Plan or plan subject to Similar Law is in no respect a representation by us or any of our affiliates or representatives that such an investment meets all relevant legal requirements with respect to investments by Plans generally or any particular Plan, or

September 2010 Page 4

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that such an investment is appropriate for Plans generally or any particular Plan. However, individual retirement accounts, individual retirement annuities and Keogh plans, as well as employee benefit plans that permit participants to direct the investment of their accounts, will not be permitted to purchase or hold the LASERS if the account, plan or annuity is for the benefit of an employee of Citigroup Global Markets Inc., Morgan Stanley or Morgan Stanley Smith Barney LLC (“MSSB”) or a family member and the employee receives any compensation (such as, for example, an addition to bonus) based on the purchase of LASERS by the account, plan or annuity.
Additional considerations: Client accounts over which Citigroup Inc., Morgan Stanley, MSSB or any of their respective subsidiaries have investment discretion are not permitted to purchase the LASERS, either directly or indirectly.
Supplemental information concerning plan of distribution; conflicts of interest: The agent may distribute the LASERS through MSSB, as selected dealer, or other dealers, which may include Morgan Stanley & Co. International plc (“MSIP”) and Bank Morgan Stanley AG. MSSB, MSIP and Bank Morgan Stanley AG are affiliates of Morgan Stanley. Selected dealers, including MSSB, and their financial advisors will collectively receive from the agent, MS & Co., a fixed sales commission of $0.11425 for each LASERS they sell. MS & Co. is our wholly-owned subsidiary. MS & Co. will conduct this offering in compliance with the requirements of NASD Rule 2720 of the Financial Industry Regulatory Authority, Inc., which is commonly referred to as FINRA, regarding a FINRA member firm’s distribution of the securities of an affiliate and related conflicts of interest. MS & Co. or any of our other affiliates may not make sales in this offering to any discretionary account. See “Plan of Distribution (Conflicts of Interest)” and “Use of Proceeds and Hedging” in the accompanying prospectus supplement for LASERS.
Contact: Morgan Stanley Smith Barney clients may contact their local Morgan Stanley Smith Barney branch office or our principal executive offices at 1585 Broadway, New York, New York 10036 (telephone number (866) 477-4776). All other clients may contact their local brokerage representative. Third-party distributors may contact Morgan Stanley Structured Investment Sales at (800) 233-1087.

This is a summary of the terms and conditions of the LASERS. We encourage you to read the accompanying prospectus supplement for LASERS and prospectus for this offering, which can be accessed via the hyperlinks on the front page of this document.

September 2010 Page 5

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Hypothetical Payments on the LASERS at Maturity

The following table illustrates the return on the LASERS and the payment at maturity for a range of hypothetical percentage changes in the final index value, depending on whether or not the closing value of the underlying index has declined to or below the downside threshold value on any index business day during the period from but excluding the pricing date to and including the valuation date. The table below is based on the following values:

Stated principal amount: $10.00
Hypothetical initial index value: 3,000
Hypothetical downside threshold value: 2,250 (75% of the hypothetical initial index value)
Maximum payment at maturity: $12.00 (120% of the stated principal amount)
Fixed percentage: 10%
Final Index Value Underlying Index Return Downside threshold value has NOT been reached Downside threshold value has been reached*
Return on LASERS Payment at Maturity Return on LASERS Payment at Maturity
6,000 100.00% 20.00% $12.00 20.00% $12.00
5,700 90.00% 20.00% $12.00 20.00% $12.00
5,400 80.00% 20.00% $12.00 20.00% $12.00
5,100 70.00% 20.00% $12.00 20.00% $12.00
4,800 60.00% 20.00% $12.00 20.00% $12.00
4,500 50.00% 20.00% $12.00 20.00% $12.00
4,200 40.00% 20.00% $12.00 20.00% $12.00
3,900 30.00% 20.00% $12.00 20.00% $12.00
3,600 20.00% 20.00% $12.00 20.00% $12.00
3,450 15.00% 15.00% $11.50 15.00% $11.50
3,300 10.00% 10.00% $11.00 10.00% $11.00
3,150 5.00% 10.00% $11.00 5.00% $10.50
3,000 0.00% 10.00% $11.00 0.00% $10.00
2,850 -5.00% 10.00% $11.00 -5.00% $9.50
2,700 -10.00% 10.00% $11.00 -10.00% $9.00
2,550 -15.00% 10.00% $11.00 -15.00% $8.50
2,400 -20.00% 10.00% $11.00 -20.00% $8.00
2,250 -25.00% 10.00% $11.00 -25.00% $7.50
2,100 -30.00% N/A N/A -30.00% $7.00
1,800 -40.00% N/A N/A -40.00% $6.00
1,500 -50.00% N/A N/A -50.00% $5.00
1,200 -60.00% N/A N/A -60.00% $4.00
900 -70.00% N/A N/A -70.00% $3.00
600 -80.00% N/A N/A -80.00% $2.00
300 -90.00% N/A N/A -90.00% $1.00
0 -100.00% N/A N/A -100.00% $0.00
  • In the scenario where the downside threshold value has been reached, the closing value of the underlying index will need to recover by the valuation date to a level higher than the initial index value in order for investors to receive a payment at maturity that exceeds the stated principal amount of the LASERS.

September 2010 Page 6

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Index LeAding StockmarkEt Return Securities

Hypothetical Examples of the Amount Payable at Maturity

The examples below illustrate how the payment at maturity on the LASERS is calculated and are based on the following terms:

Stated principal amount: $10.00
Hypothetical initial index value: 3,000
Hypothetical downside threshold value: 2,250 (75% of the hypothetical initial index value)
Maximum payment at maturity: $12.00 (120% of the stated principal amount)
Fixed percentage: 10%

EXAMPLE 1: Downside threshold value has NOT been reached and the underlying index appreciates

The closing value of the underlying index is greater than the downside threshold value on each index business day during the period from but excluding the pricing date to and including the valuation date, and the final index value is higher than the initial index value by 25%.

Hypothetical final index value = 3,750
Index percent change = (final index value – initial index value) / initial index value
= (3,750 – 3,000) / 3,000
= 25%
Index return amount = stated principal amount x [the greater of (i) index percent change and (ii) fixed percentage]
= $10.00 x 25%
= $2.50
Payment at maturity = stated principal amount + index return amount
= $10.00 + $2.50
= $12.50, subject to the maximum payment at maturity of $12.00
Payment at maturity = $12.00

EXAMPLE 2: Downside threshold value has NOT been reached and the underlying index declines

The closing value of the underlying index is greater than the downside threshold value on each index business day during the period from but excluding the pricing date to and including the valuation date, and the final index value is lower than the initial index value by 20%.

Hypothetical final index value = 2,400
Index percent change = (final index value – initial index value) / initial index value
= (2,400 – 3,000) / 3,000
= –20%
Index return amount = stated principal amount x [the greater of (i) index percent change and (ii) fixed percentage]
= $10.00 x 10.00%
= $1.00
Payment at maturity = stated principal amount + index return amount
= $11.00, subject to the maximum payment at maturity of $12.00
Payment at maturity = $11.00

EXAMPLE 3: Downside threshold value has been reached and the underlying index declines

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The closing value of the underlying index was less than or equal to the downside threshold value on one or more index business days during the period from but excluding the pricing date to and including the valuation date, and the final index value is lower than the initial index value by 50%.

Hypothetical final index value = 1,500
Index percent change = (final index value – initial index value) / initial index value
= (1,500 – 3,000) / 3,000
= –50%
Index return amount = stated principal amount x index percent change
= $10.00 x (–50%)
= –$5.00
Payment at maturity = stated principal amount + index return amount, which means that the payment at maturity is an amount less than the stated principal amount, because the index return amount is negative.
= $10.00 + (–$5.00)
= $5.00, subject to the maximum payment at maturity of $12.00
Payment at maturity = $5.00

EXAMPLE 4: Downside threshold value has been reached but the underlying index recovers to appreciate

The closing value of the underlying index was less than or equal to the downside threshold value on one or more index business days during the period from but excluding the pricing date to and including the valuation date; however, the underlying index has subsequently recovered and the final index value is higher than the initial index value by 10%.

Hypothetical final index value = 3,300
Index percent change = (final index value – initial index value) / initial index value
= (3,300 – 3,000) / 3,000
= 10%
Index return amount = stated principal amount x index percent change
= $10.00 x 10%
= $1.00
Payment at maturity = stated principal amount + index return amount
= $10.00 + $1.00
= $11.00, subject to the maximum payment at maturity of $12.00
Payment at maturity = $11.00

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Payment at Maturity

At maturity, investors will receive for each $10 stated principal amount of LASERS that they hold a payment equal to the sum of the stated principal amount and an index return amount, subject to a maximum payment at maturity of $12.00 per LASERS . The index return amount may be positive, zero or negative.

If the closing value of the underlying index is greater than the downside threshold value on each index business day during the period from but excluding the pricing date to and including the valuation date, the index return amount will be positive and will equal:

$10 × [the greater of (x) index percent change and (y) fixed percentage]

where,

index percent change =

initial index value = 2,774.62, which is the index closing value on the pricing date
final index value = The index closing value on the valuation date
downside threshold value = 2,080.965, which is 75% of the initial index value
maximum payment at maturity = $12.00
fixed percentage = 10%

If the closing value of the underlying index is less than or equal to the downside threshold value on any index business day during the period from but excluding the pricing date to and including the valuation date, the index return amount will equal:

$10 × index percent change

If the final index value is less than the initial index value, the index return amount will be negative and the payment at maturity will be less, and may be significantly less, than the stated principal amount. There is no minimum payment at maturity on the LASERS, and, accordingly, you could lose your entire investment.

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Risk Factors

The following is a non-exhaustive list of certain key risk factors for investors in the LASERS. For further discussion of these and other risks, you should read the section entitled “Risk Factors” in the accompanying prospectus supplement for LASERS and the accompanying prospectus. You should also consult with your investment, legal, tax, accounting and other advisers in connection with your investment in the LASERS.

§ LASERS do not pay interest or guarantee return of principal. The terms of the LASERS differ from those of ordinary debt securities in that the LASERS do not pay interest and do not guarantee the return of any of the principal amount at maturity. If the closing value of the underlying index is less than or equal to the downside threshold value on any index business day during the period from but excluding the pricing date to and including the valuation date and the final index value is less than the initial index value, the payout at maturity will be an amount in cash that is less than the $10 stated principal amount of each LASERS by an amount proportionate to the decrease in the final index value from the initial index value. There is no minimum payment at maturity on the LASERS, and, accordingly, you could lose your entire investment.

§ Appreciation potential is limited by the maximum payment at maturity. The appreciation potential of the LASERS is limited by the maximum payment at maturity of $12.00 per LASERS, or 120% of the stated principal amount. Because the payment at maturity will be limited to 120% of the stated principal amount for the LASERS, any increase in the final index value over the initial index value by more than 20% of the initial index value will not further increase the return on the LASERS.

§ You will not benefit from the fixed percentage if the downside threshold value is reached. If the closing value of the underlying index is less than or equal to the downside threshold value on any index business day during the period from but excluding the pricing date to and including the valuation date, the payment at maturity will solely depend on the closing value of the underlying index on the valuation date and, accordingly, you will lose the benefit of the limited protection against the loss of principal based on the fixed percentage of 10%. As a result, you will be exposed on a 1 to 1 basis to any decline in the closing value of the underlying index on the valuation date.

§ Market price of the LASERS may be influenced by many unpredictable factors. Several factors will influence the value of the LASERS in the secondary market and the price at which MS & Co. may be willing to purchase or sell the LASERS in the secondary market, including: the value, volatility and dividend yield of the underlying index, whether the downside threshold value has been reached, interest and yield rates in the market, time remaining to maturity, geopolitical conditions and economic, financial, political and regulatory or judicial events and any actual or anticipated changes in our credit ratings or credit spreads. You may receive less, and possibly significantly less, than the stated principal amount per LASERS if you try to sell your LASERS prior to maturity.

§ The LASERS are subject to the credit risk of Morgan Stanley, and any actual or anticipated changes to its credit ratings or credit spreads may adversely affect the market value of the LASERS. You are dependent on Morgan Stanley's ability to pay all amounts due on the LASERS at maturity and therefore you are subject to the credit risk of Morgan Stanley. If Morgan Stanley defaults on its obligations under the LASERS, your investment would be at risk and you could lose some or all of your investment. As a result, the market value of the LASERS prior to maturity will be affected by changes in the market’s view of Morgan Stanley's creditworthiness. Any actual or anticipated decline in Morgan Stanley’s credit ratings or increase in the credit spreads charged by the market for taking Morgan Stanley credit risk is likely to adversely affect the market value of the LASERS.

§ The LASERS will not be listed on any securities exchange and secondary trading may be limited. The LASERS will not be listed on any securities exchange. Therefore, there may be little or no secondary market for the LASERS. MS & Co. may, but is not obligated to, make a market in the LASERS. Even if there is a secondary market, it may not provide enough liquidity to allow you to trade or sell the LASERS easily. Because we do not expect that other broker-dealers will participate significantly in the secondary market for the LASERS, the price at which you may be able to trade your LASERS is likely to depend on the price, if any, at which MS & Co. is willing to transact. If, at any time, MS & Co. were not to make a market in the LASERS, it is likely that there would be no secondary market for the LASERS. Accordingly, you should be willing to hold your LASERS to maturity.

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§ Adjustments to the underlying index could adversely affect the value of the LASERS. The underlying index publisher may discontinue or suspend calculation or publication of the underlying index at any time. In these circumstances, the calculation agent will have the sole discretion to substitute a successor index that is comparable to the discontinued underlying index and is not precluded from considering indices that are calculated and published by the calculation agent or any of its affiliates.

§ The inclusion of commissions and projected profit from hedging in the original issue price is likely to adversely affect secondary market prices. Assuming no change in market conditions or any other relevant factors, the price, if any, at which MS & Co. is willing to purchase the LASERS at any time in secondary market transactions will likely be significantly lower than the original issue price, since secondary market prices are likely to exclude commissions paid with respect to the LASERS and the cost of hedging our obligations under the LASERS that are included in the original issue price. The cost of hedging includes the projected profit that our subsidiaries may realize in consideration for assuming the risks inherent in managing the hedging transactions. These secondary market prices are also likely to be reduced by the costs of unwinding the related hedging transactions. Our subsidiaries may realize a profit from the expected hedging activity even if investors do not receive a favorable investment return under the terms of the LASERS or in any secondary market transaction. In addition, any secondary market prices may differ from values determined by pricing models used by MS & Co., as a result of dealer discounts, mark-ups or other transaction costs.

§ Hedging and trading activity by our subsidiaries could potentially adversely affect the value of the LASERS. One or more of our subsidiaries have carried out, and will continue to carry out, hedging activities related to the LASERS (and possibly to other instruments linked to the underlying index or its component stocks), including trading in the stocks that constitute the underlying index as well as in other instruments related to the underlying index. Some of our subsidiaries also trade the stocks that constitute the underlying index and other financial instruments related to the underlying index on a regular basis as part of their general broker-dealer and other businesses. Any of these hedging or trading activities on or prior to the pricing date could have increased the initial index value and, therefore, could have increased the level above which the index closing value must remain so that the downside threshold value is not reached and, if the downside threshold value is reached, could have increased the level at which the index closing value must be on the valuation date before you would receive at maturity a payment that exceeds the stated principal amount of the LASERS. Additionally, such hedging or trading activities during the term of the LASERS, including on the valuation date, could adversely affect the final index value and, accordingly, the amount of cash an investor will receive at maturity.

§ The calculation agent, which is a subsidiary of the issuer, will make determinations with respect to the LASERS. As calculation agent, MS & Co. has determined the initial index value and will determine the final index value, whether the index closing value has declined to or below the downside threshold value on any index business day during the period from but excluding the pricing date to and including the valuation date, and will calculate the amount of cash you will receive at maturity. Any of these determinations made by MS & Co., in its capacity as calculation agent, including with respect to the occurrence or non-occurrence of market disruption events and the selection of a successor index or calculation of the final index value in the event of a discontinuance of the underlying index, may adversely affect the payout to you at maturity.

§ The U.S. federal income tax consequences of an investment in the LASERS are uncertain. Please read the discussion under “Fact Sheet ― General Information ― Tax considerations” in this document and the discussion under “United States Federal Taxation” in the accompanying prospectus supplement for LASERS (together the “Tax Disclosure Sections”) concerning the U.S. federal income tax cons equences of an investment in the LASERS . If the Internal Revenue Service (the “IRS”) were successful in asserting an alternative treatment, the timing and character of income on the LASERS might differ significantly from the tax treatment described in the Tax Disclosure Sections. For example, under one treatment, U.S. Holders could be required to accrue original issue discount on the LASERS every year at a “comparable yield” determined at the time of issuance and recognize all income and gain in respect of the LASERS as ordinary income. Because the LASERS provide for the return of principal except where the value of the underlying index declines to or below the downside threshold value, the risk that they would be recharacterized, for U.S. federal income tax purposes, as debt instruments giving rise to ordinary income, rather than as an open transaction, is higher than with other equity-linked securities that do not provide for the return of principal. The issuer does not plan to request a ruling from the IRS regarding the tax treatment of the LASERS , and the IRS or a court may not agree with the tax treatment described in the Tax Disclosure Sections. On December 7, 2007, the Treasury Department and the IRS released a notice requesting comments on the U.S. federal income tax treatment of “prepaid forward contracts” and similar instruments, such as the LASERS. The

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notice focuses in particular on whether to require holders of these instruments to accrue income over the term of their investment. It also asks for comments on a number of related topics, including the character of income or loss with respect to these instruments; whether short-term instruments should be subject to any such accrual regime; the relevance of factors such as the exchange-traded status of the instruments and the nature of the underlying property to which the instruments are linked; the degree, if any, to which income (including any mandated accruals) realized by non-U.S. investors should be subject to withholding tax; and whether these instruments are or should be subject to the “constructive ownership” regime, which very generally can operate to recharacterize certain long-term capital gain as ordinary income that is subject to an interest charge. While the notice requests comments on appropriate transition rules and effective dates, any Treasury regulations or other guidance promulgated after consideration of these issues could materially and adversely affect the tax consequences of an investment in the LASERS, possibly with retroactive effect. Both U.S. and Non-U.S. Holders should consult their tax advisers regarding the U.S. federal income tax consequences of an investment in the LASERS, including possible alternative treatments, the issues presented by this notice and any tax consequences arising under the laws of any state, local or foreign taxing jurisdiction.

Information about the Underlying Index

The Dow Jones EURO STOXX 50 ® Index. The Dow Jones EURO STOXX 50 ® Index was created by STOXX Limited, a joint venture between Deutsche Börse AG, Dow Jones & Company, Inc. and SWX Swiss Exchange. Publication of the Dow Jones EURO STOXX 50 ® Index began on February 26, 1998, based on an initial index value of 1,000 at December 31, 1991. The Dow Jones EURO STOXX 50 ® Index is composed of 50 component stocks of market sector leaders from within the Dow Jones STOXX 600 Supersector Indices, which includes stocks selected from the Eurozone. The component stocks have a high degree of liquidity and represent the largest companies across all market sectors. For additional information, please see “Annex A—Underlying Indices and Underlying Index Publishers Information––Dow Jones Euro STOXX 50 ® Index” in the accompanying prospectus supplement for LASERS.

License Agreement between STOXX Limited and Morgan Stanley. “Dow Jones EURO STOXX ® ” and “STOXX ® ” are registered trademarks of STOXX Limited and have been licensed for use for certain purposes by Morgan Stanley. See “Annex A—Underlying Indices and Underlying Index Publishers Information––Dow Jones Euro STOXX 50 ® Index––License Agreement between STOXX Limited and Morgan Stanley” in the accompanying prospectus supplement for LASERS.

Historical Information

The following table sets forth the published high and low index closing values, as well as end-of-quarter index closing values, of the underlying index for each quarter in the period from January 1, 2005 through September 28, 2010. The graph following the table shows the daily closing values of the underlying index for the same period. The index closing value of the underlying index on September 28, 2010 was 2,774.62. We obtained the information in the table below from Bloomberg Financial Markets without independent verification. The historical performance of the underlying index should not be taken as an indication of its future performance, and no assurance can be given as to the performance of the underlying index on the valuation date or during the term of the LASERS.

Dow Jones EURO STOXX 50 ® Index High Low Period End
2005
First Quarter 3,114.54 2,924.01 3,055.73
Second Quarter 3,190.80 2,930.10 3,181.54
Third Quarter 3,429.42 3,170.06 3,428.51
Fourth Quarter 3,616.33 3,241.14 3,578.93
2006
First Quarter 3,874.61 3,532.68 3,853.74
Second Quarter 3,890.94 3,408.02 3,648.92
Third Quarter 3,899.41 3,492.11 3,899.41

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Dow Jones EURO STOXX 50 ® Index High Low Period End
Fourth Quarter 4,140.66 3,880.14 4,119.94
2007
First Quarter 4,272.32 3,906.15 4,181.03
Second Quarter 4,556.97 4,189.55 4,489.77
Third Quarter 4,557.57 4,062.33 4,381.71
Fourth Quarter 4,489.79 4,195.58 4,399.72
2008
First Quarter 4,339.23 3,431.82 3,628.06
Second Quarter 3,882.28 3,340.27 3,352.81
Third Quarter 3,445.66 3,000.83 3,038.20
Fourth Quarter 3,113.82 2,165.91 2,447.62
2009
First Quarter 2,578.43 1,809.98 2,071.13
Second Quarter 2,537.35 2,097.57 2,401.69
Third Quarter 2,899.12 2,281.47 2,872.63
Fourth Quarter 2,992.08 2,712.30 2,964.96
2010
First Quarter 3,017.85 2,631.64 2,931.16
Second Quarter 3,012.65 2,488.50 2,573.32
Third Quarter (through September 28, 2010) 2,827.27 2,507.83 2,774.62

Dow Jones EURO STOXX 50 ® Index Daily Index Closing Values January 1, 2005 to September 28, 2010

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Where You Can Find More Information

Morgan Stanley has filed a registration statement (including a prospectus, as supplemented by the prospectus supplement for LASERS) with the Securities and Exchange Commission, or SEC, for the offering to which this pricing supplement relates. You should read the prospectus in that registration statement, the prospectus supplement for LASERS and any other documents relating to this offering that Morgan Stanley has filed with the SEC for more complete information about Morgan Stanley and this offering. You may get these documents without cost by visiting EDGAR on the SEC web site at . . www.sec.gov. Alternatively, Morgan Stanley will arrange to send you the prospectus and the prospectus supplement for LASERS if you so request by calling toll-free 800-584-6837.

You may access these documents on the SEC web site at . . www.sec.gov as follows:

EFPlaceholder Prospectus Supplement for LASERS dated February 23, 2010

EFPlaceholder Prospectus dated December 23, 2008

Terms used in this pricing supplement are defined in the prospectus supplement for LASERS or in the prospectus. As used in this pricing supplement, the “Company,” “we,” “us” and “our” refer to Morgan Stanley.

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