Lepu Biopharma Co., Ltd. — Proxy Solicitation & Information Statement 2023

Aug 9, 2023

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LEPU BIOPHARMA CO., LTD. 樂普生物科技股份有限公司

(A joint stock company incorporated in the People’s Republic of China with limited liability)

(Stock Code: 2157)

PROXY FORM FOR USE AT THE 2023 FIRST EXTRAORDINARY GENERAL MEETING

I/We [(Note][1)] of

being the registered holder(s) of [(Note][2)] shares of RMB1.00 each in the share capital of Lepu Biopharma Co., Ltd. (the “ Company ”) HEREBY APPOINT THE CHAIRMAN OF THE EGM or [(Note][3)] of

as my/our proxy to attend and act for me/us at the 2023 first extraordinary general meeting of the Company to be held at Conference Room, Building 7, No. 37 Chaoqian Road, Changping District, Beijing, the PRC on August 25, 2023 (Friday) at 11:30 a.m. (the “ EGM ”) (and any adjournment thereof) for the purposes of considering and, if thought fit, passing the resolutions as set out in the notice convening the EGM and at the EGM (and at any adjournment thereof) to vote for me/us and in my/our name(s) in respect of the resolution as indicated below [(Note][4)] .

SPECIAL RESOLUTIONS FOR(Note 4) AGAINST(Note 4) ABSTAIN(Note 4) 1. To consider and approve the proposed extension of the validity period of the resolutions in relation to the proposed Issue of A Shares and listing on the Sci-Tech Board for further 12 months. 2. To consider and approve the proposed extension of the validity period of the resolution authorizing the Board of Directors and persons authorized by it to fully handle the relevant matters in connection with the Issue of A Shares and listing on the Sci-Tech Board for further 12 months.

Date:

Signature(s) [(Note][5)] :

Notes:

1. Please insert full name(s) and address(es) as shown in the register of members of the Company in BLOCK CAPITALS . 2. Please insert the number of shares registered in your name(s) and type of shares (Domestic shares or H shares) to which this proxy form relates. If no number of shares is inserted, this proxy form will be deemed to relate to all shares registered in your name(s). 3. If any proxy other than the Chairman of the EGM is preferred, strike out the words “ THE CHAIRMAN OF THE EGM or” and insert the name and address of the proxy desired in the space provided. A shareholder entitled to attend and vote at the EGM may appoint one or more proxies to attend and vote in his stead. A proxy need not be a shareholder of the Company but must attend the EGM in person to represent you. ANY ALTERATION MADE TO THIS PROXY FORM MUST BE INITIALLED BY THE PERSON(S) WHO SIGNS IT. 4. IMPORTANT: IF YOU WISH TO VOTE FOR A RESOLUTION, TICK ( � ) IN THE RELEVANT BOX BELOW THE BOX MARKED “FOR”. IF YOU WISH TO VOTE AGAINST A RESOLUTION, TICK ( � ) IN THE RELEVANT BOX BELOW THE BOX MARKED “AGAINST”. If no direction is given, your proxy may vote or abstain at his discretion. Your proxy will also be entitled to vote or abstain at his discretion on any resolution properly put to the EGM other than that referred to in the notice convening the EGM.

2. This proxy form must be signed by you or your attorney duly authorized in writing. In case of a corporation, the same must be executed either under its common seal or under the hand of its director(s) or duly authorized attorney. If the proxy form is signed by an attorney of the shareholder, the power of attorney authorizing that attorney to sign or other authorization document must be notarized.

3. In case of joint holders of any shares, any one of such joint holders may vote at the EGM, either in person or by proxy, in respect of such shares as if he is solely entitled thereto. However, if more than one of such joint holders are present at the EGM, in person or by proxy, the vote of the joint holder whose name stands first on the register of members, whether in person or by proxy, will be accepted to the exclusion of the votes of other joint holder(s).

4. In order to be valid, the instrument appointing a proxy together with the power of attorney or other authority, if any, under which it is signed, or a notarially certified copy of such power of attorney or authority, must be completed and returned to the Company’s head office and principal place of business in the PRC, at No. 651, Lianheng Road, Minhang District, Shanghai, PRC (for holders of Domestic Shares) or the H Share registrar of the Company in Hong Kong, Computershare Hong Kong Investor Services Limited, at 17M Floor, Hopewell Centre, 183 Queen’s Road East, Wanchai, Hong Kong (for holders of H shares), at least 24 hours before the EGM (i.e. before 11:30 a.m. on Thursday, August 24, 2023) or any adjourned meeting thereof. Completion and return of the form of proxy will not preclude a shareholder from attending and voting at the EGM or any adjourned meeting thereof should he/she so wish.

5. Shareholders or their proxies attending the EGM (and any adjournment thereof) shall produce their identity documents.

PERSONAL INFORMATION COLLECTION STATEMENT

Yourrequestsupplyfor theof appointmentyour and yourof proxy’sa proxy(or(orproxies’)proxies) andname(s)your andvotingaddress(es)instructionsis onfora thevoluntarymeetingbasisof theforCompanythe purpose(theof“ Purposes processing”).yourWe may transfer your and your proxy’s (or proxies’) name(s) and address(es) to our agent, contractor, or third party service provider who provides administrative, computer and other services to us for use in connection with the Purposes and to such parties who are authorized by law to request the information or are otherwise relevant for the Purposes and need to receive the information. Your and your proxy’s (or proxies’) name(s) and address(es) will be retained for such period as may be necessary to fulfil the Purposes. Request for access to and/or correction of the relevant personal data can be made in accordance with the provisions of the Personal Data (Privacy) Ordinance and any such request should be in writing by mail to the Company/Computershare Hong Kong Investor Services Limited at the above address.