ILLUMINA, INC. — Director's Dealing 2011

Feb 24, 2011

SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: ILLUMINA INC (ILMN)
CIK: 0001110803
Period of Report: 2011-02-22

Reporting Person: HENRY CHRISTIAN O (Sr VP & CFO)

Non-Derivative Transactions

Date	Security	Code	Shares	Price	A/D	Holdings After	Ownership
2011-02-22	Common Stock	M	2894	$5.23	Acquired	32349	Direct
2011-02-22	Common Stock	S	2894	$70.8	Disposed	29455	Direct
2011-02-22	Common Stock	M	2106	$5.23	Acquired	31561	Direct
2011-02-22	Common Stock	S	2106	$71.7237	Disposed	29455	Direct
2011-02-22	Common Stock	M	4260	$20.04	Acquired	33715	Direct
2011-02-22	Common Stock	S	4260	$70.7952	Disposed	29455	Direct
2011-02-22	Common Stock	M	3240	$20.04	Acquired	32695	Direct
2011-02-22	Common Stock	S	3240	$72.07	Disposed	29455	Direct
2011-02-22	Common Stock	M	3085	$32.485	Acquired	32540	Direct
2011-02-22	Common Stock	S	3085	$70.8442	Disposed	29455	Direct
2011-02-22	Common Stock	M	1915	$32.485	Acquired	31370	Direct
2011-02-22	Common Stock	S	1915	$71.7702	Disposed	29455	Direct

Derivative Transactions

Date	Security	Exercise Price	Code	Shares	A/D	Expiration	Underlying	Ownership
2011-02-22	Non-Qualified Stock Option (right to buy)	$5.23	M	5000	Disposed	2015-06-06	Common Stock (5000)	Direct
2011-02-22	Non-Qualified Stock Option (right to buy)	$20.04	M	7500	Disposed	2017-01-25	Common Stock (7500)	Direct
2011-02-22	Non-Qualified Stock Option (right to buy)	$32.485	M	5000	Disposed	2018-01-29	Common Stock (5000)	Direct

Footnotes

F1: The sale was made pursuant to a 10b5-1 plan.

F2: Weighted average sale price representing 2,894 shares sold ranging from $70.33 to $71.26 per share. Number of shares sold at each separate price will be made available to the SEC staff, the issuer, or a security holder of the issuer upon request.

F3: Weighted average sale price representing 2,106 shares sold ranging from $71.39 to $72.07 per share. Number of shares sold at each separate price will be made available to the SEC staff, the issuer, or a security holder of the issuer upon request.

F4: Weighted average sale price representing 4,260 shares sold ranging from $70.35 to $71.21 per share. Number of shares sold at each separate price will be made available to the SEC staff, the issuer, or a security holder of the issuer upon request.

F5: Weighted average sale price representing 3,240 shares sold ranging from $71.36 to $72.07 per share. Number of shares sold at each separate price will be made available to the SEC staff, the issuer, or a security holder of the issuer upon request.

F6: Weighted average sale price representing 3,085 shares sold ranging from $70.45 to $71.40 per share. Number of shares sold at each separate price will be made available to the SEC staff, the issuer, or a security holder of the issuer upon request.

F7: Weighted average sale price representing 1,915 shares sold ranging from $71.45 to $72.06 per share. Number of shares sold at each separate price will be made available to the SEC staff, the issuer, or a security holder of the issuer upon request.