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Evotec SE — Investor Presentation 2012
Mar 24, 2012
151_ip_2012-03-24_4f9b5883-ab02-4e47-9fc5-aa31e2586e0f.pdf
Investor Presentation
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Evotec AG , Full-Year Results 2011 , Frankfurt, 20th March 2012
Forward-looking s statements
Information set forth in this presen forward-looking statements, which invo risks and uncertainties ncertainties. The forward forward-lo contained herein represent the judgemen the date of this presentation. Such statements are neither promises nor gua subject to a variety of risks and uncert which are beyond our control control, and wh ntation containsolve a number ofoking statements nt of Evotec as offorward-looking arantees, but are tainties, many of hich couldcause
actual results to differ materially from those contemplated in these forward-looking statements. We expressly disclaim an obligation or ndertaking to release p blicl any undertakingpublicly any updates or revisions to any such statements to reflect any change in our expectations or any change in events, conditions or circumstances on which any such statement is based.
Welcome to Evoteec!
Your management team
Agenda
· Highlights 2011
- Action Plan 2016 Innovation Efficiency
- Operational & Financial Performance 2011
- Growth Outlook
A very good year, with a strong outlook for 2012
Key themes & Highlights 2 2011
| S h t t r o n g g r o w |
f 4 % l i h € 8 8 0 2 0 4 % i i b i l i h € 2 5 t t t t t t t t 5 o p n e g r o o m o p e r a n g p r o a g r o o m w y w • - , , f 4 4 % i € 1 0 i i i h l t t g r o s s m a r g n m p o s e o p e r a n g c a s o ; v w S f d b k d i l i i i d i t t t t t r o n g o r e r o o a n m e s o n e o p p o r n e s n c a e r e e n e s o u v u • € 8 8 € 9 0 i 2 0 1 2 m m n – |
|---|---|
| P i l i i t h t p e n e w o u t e x p o s u r e o f i i l i k n a n c a r s |
S f i i i i i i P h I I I d P h I I d t t t t t g n c a n n e a r- e r m o p p o o r n e s n a s e a n a s e p r o c u u • d l h i t t e v e o p m e n p a r n e r s p s s f B d l i l i 0 5 t t t r o a o n g e r m p p e n e o o a r g e s • - ~ |
| M k t a r e l i d i t c o n s o a o n |
S f S ( C ) l M & A i h E F i d F d E t t t t c c e s s o e c a n r a n c s c o o m p o n o c s a n o e c u u w v u u v • ) 1 ( ) M i h K i f € 2 6 6 6 u n c n a x o o r m f L h l d i d i i i h i t t t t t t t t t a r g e s e c n o o g a n n r a s r c r e p g r a e n n e e s s m m e e n n n c o m p a n s o r y u u u v v y y • i i i d € 1 0 t t n a e a p p r o x m , |
| F F i i t t i i l l r s n c a s s - - i t i n n o v a o n |
F F d d i i i i h i i i h h l l i i i i d d i i h d t t t t t t o c s e n e s m e n s n g n n o a e s c o e r r e s e a r c a r e a s a n u v y v v v y • d i l l i € 8 4 a c a e m c a a n c e s a p p r o o x m , |
Promised and delivered!
Completion of Action Plan 2012 (from 04/2009 - 03/2012)
A good starting point for further growth
Completion of Action Plan 2012 (from $04/2009 - 03/2012$ )
2) Acquisition of Zebrafish technology (UK); 5) Acquisition of Compound Focus (Evotec San Francisco) 3) Acquisition of Develogen (Evotec Goettingen)
Revenue guidance discovery alliance e was increased 2x following better e business and EVT 302 upfront
Overview financial guidan nce 2011
| i € n m |
|||||
|---|---|---|---|---|---|
| 2 0 1 0 |
1 ) 2 0 1 1 |
∆ | G i d u a n c e 2 ) S S t t b b e p e m e r |
G i d u a n c e M M h h a r c |
|
| R e v e n u e s |
5 5 |
8 0 |
4 % 5 + |
9 7 7 7 - |
6 4 6 6 – |
| R & D e p e n s e s x |
6 1 |
8 4 |
3 8 % + |
1 0 ~ |
1 0 ~ |
| O i i t p e r a n g n c o m e |
1 7 |
2 5 |
2 0 4 % + |
I d m p r o e o e r v v 2 0 1 0 |
I d m p r o e o e r v v 2 0 1 0 |
| i i d i d L t t q u y a y e a r e n |
7 0 |
3 ) 6 2 |
6 0 > |
6 5 ~ |
- 7 1) 2011 incl. Kinaxo from April and incl. Compound Focus from June onwards
- 2) Guidance adjusted with publication of partnering of EV VT 302 with Roche
- 3) In 2011 a total of € 16.6m was spent in cash for acquisit ions incl. earn-out payments
Agenda
- •Highlights 2011
- • Action Plan 2016 – Innovation Efficiency
- • Operational & Financial Performance 2011
- •Growth Outlook
Dramatic decline in R&D productivity
Macro starting points – Er room´s law in Pharmaceutical R&D
Industry starts to a productivity throu appreciate increased gh external innovation
Customer starting points
Innovation efficienpharma and biotec ncy will be the driver for ch in the next decade
Action Plan 2016 - Forcesat work
Evo g as t e g o lving the glo Innovation Efficienoba eade l leader in ncy
Goals and controlling of A Action Plan 2016
Key Performance Indicators
| G r o w |
D b l l b 2 0 1 6 t t o e r e e n e s a e s u v u y • O i I i f f 1 5 % t t p e r a n g n c o m e a a m a r g n o a p p r r o o r e e n e s x v u • I l i f i h h l i l d i i l b 2 0 1 6 t t t t t t m p r o e q a o r e e n e m r o g g r o a m e s o n e a n s e r c e n c o m e a e s v u y v u x u y y, v y • |
|---|---|
| I t n n o v a e |
C i i € 1 0 i h i h l i i d h t t t t t o n n e o n e s a a p p p p r r o o m p p a a a n g n n o a e n p a r n e r e r e s e a r c u v x x y v v u • ( f ) d l l l l l i l l l d i t e g e x p a n r o m s m a m o e c u e s a s s o n o a r g e m o e c u e s c o v e r y C i d h l i f b € 1 0 t t t t t o n n e o p g r a e e c n o o g n r a s r c r e s a p p r o m p a u u y u u y x • f f B B i i l l d d i i l l i i i i h h i i i i l l i i k k h h h h h i h l l l i i i i t t t t t t t t t t t t u e v e n m o r e m a u r e p p e n e w o u n a n c a r s r o u g g y s e e c v e p a r n e r n g • |
| C & t r e a e C l i d t o n s o a e |
A i l i i i i k l i d i t t t t t t t c e p a r c p a e n s r a e g c m a r e e c o n s o a o n v y • O i i h h l d l i t t p m s e s a r e o e r a e c r e a o n v u • |
Leveraging innovation efficient discovery
Action Plan 2016 - Evotec's offering for Innovation Efficiency
Broad stand alonee execution business
Comprehensive Drug Disc covery Platform – "EVO Apps"
Disease biology is the processor for integrated drug discovery alliances
Alliance model
"Faster to Decisioimproves innovati ns" business model on efficiency
Business model
Combining g leading platforms with wo gg y dru discovery rld class science
Accelerating process for fi rst-in-class innovation
| F o c s u |
I t t n e g r a e |
E i n g n e e e r |
S c r e e n |
|
|---|---|---|---|---|
| d i s e a s e f d i i m o y n g h i m e c a n s m s |
i e m e r g n g i i h t i n s g s n d i b i l s e a s e o o g y |
d l i t h m o e s s w h i h g e r d i t b i l i t p r e c a a y |
t t i l l s s e m a c a y y , & b i d u n a s e h i c o m p r e e n s v e |
|
| C f l b i t t e a r e n e o • i t t p a e n s O O b b i i o s v u • d i f f i i t t t e r e n a o n o i i h i t t e x s n g e r a p e s T b l i d t r a c a e n r g u • d i s c o e r p r o c e s s v y |
A l i i h k t g n w e y • i i l d i o p n o n e a e r s n d i a c a e m a E b l i h t s a s n e w • l l b i t c o a o r a o n d l m o e s A i c q r e u • i i l t t n n o a e o o s v v d d t a a n n a s s e s |
R l t e e v a n c e o • h d i u m a n s s e a s e P P i i i i t t r o m o x y • d i i f i s e a s e s s p e c c h i m e c a n s s m C b i H C o m n e • d i h t t r e a o s u w h h t t r o g p u u u |
L e v e r a g e • d i d l s e a s e m o e s f d t t o r a r g e s a n d c o m p o n s u A i d b i d v o a s e • h a p p r o a c e s C h i o m p r e e n s e v • d t t a a s e s i d i i m p r o e e c s o n v k i m a n g |
A l d i t i r e a e s n g y x i i t i t i n a v e s : C B t r e e a u C C N N h h r e e p r o n u f P t t i l t o e n a u u r e i i t i t i n a v e s C P i u r e a n C N r e e r o n u u C I f l i t u r e n a m m a o n C H t u r e e a r … |
Systematic, unbias mechanism-focusesed and comprehensive ed infrastructures
Accelerating first-in-class drug discovery innovation
| H i h g l l i i t t r e s o o n u i e x p r e s s o n l i a n a y s s |
/ T i l i t t r a n s c r p o m e p r o e o m e a n a y s s • P P f f i i l l i i f f i i f f i i l l l l d d i i t r o n g o s p e c c c e s a n s s e s u • D i l h i t s e a s e r e e a n m e c a n s m s v − S d l i f d i i t a g e a n a s s o s e a s e p r o g r e s s s o n y − |
|---|---|
| M h i e c a n s m f d o c s e u h i l c e m c a i g e n o m c s |
S h i i d h i h l l l t t t t o p s c a e g c o n e n c e u a r a s s s a y • P i l l / i t r m a r y c e s s s u e s − I l i d l l t m m o r a s e c e s − f H i h i t t g c o n e n s c r e e n n g o • A d l i b i t t n n o a e r a r e s − D i l i b i v e r s e r a r e s − N N l l d d t t t t a r a p r o c s u u − |
| M h i e c a n s m f d o c u s e f i l t n c o n a u i t p r o e o m c s |
S h i i d h i h l l l t t t t o p s c a e g c o n e n c e a r a s s s a u y • L f f i ( R N A i ) t o s s o u n c o n • G i f f i ( O R F l i b ) t a n o u n c o n e o m e r a r y • H i h d t t t g c o n e n r e a o u s • |
Deep product pipe eline without financial risk
Portfolio of product develo opment partnerships
Sig p nificant portfol assets without finaio of high-value ancial risk
Update on assets
| E V T 3 0 2 |
D i P 2 7 7 a e p |
|||
|---|---|---|---|---|
| D l l i b i l i i d l l t, t t t e v e o p m e n r e g u a o r y r e s p o n s e s a n a c o s s • h b f d R h t t a v e e e n r a n s e r r e o o c e f D l i l i l l d l t t t t t t e v e o p m e n p r o e c a n p o e n a y a r g e s a n a o n e • l i i b i i t t t t t a p p c a o n o r c o m n a o n r e a m e n s L P h I I b i l i i f i 2 0 1 2 t t t t a r g e a s e r a n p r e p a r a o n o r s a r n • P h I I b l i d P h I I I d / 2 0 1 3 2 0 1 4 t t t a s e c o m p e o n a n a s e s a r e n • |
M i d i f t P h I I I i l ( B l l f i ) 1 t t s t t t e p r m a r y e n p o n o a s e r a e a c e u n c o n ; • ) 1 d d i i f i i f C i d l l t t t t t e m o n s r a e a s g n c a n p r e s e r v a o n o -p e p e e v e s d f R i 2 P h I I I i h 5 0 0 i t t n t t t e c r u m e n o a s e w a p p r o x. p a e n s • d b l d b i d 2 0 1 2 t t t e x p e c e o e c o m p e e y m t P N i l f i l l i f 1 h I I I d t t t s t e x m e s o n e u p o n n a c o m p e o n o a s e s u y • ( ) d i d l i i l d l i d 2 0 1 2 t t a n c o n n u e c n c a e v e o p m e n m ; d / ( ( ) ) F i l d f 2 P h I I I i 2 0 1 4 2 0 1 f i l t 5 t n n a a a o a s e n e r s s a e s ; • f / ( ) j d 2 0 1 2 0 1 6 t 5 p r o e c e o r e |
|||
| E V T 1 0 1 / 1 0 3 |
O h l i i l / l i i l t e r c n c a p r e -c n c a p r o g r a m m e s |
|||
| C l d l i l d f i d i d i l i d f t t t t o m p e e m u p e o s e n n g s u e s, s o s a e y • f i l p r o e |
E V T C l i i l P h I I b d f C h i i 2 0 1 t t t n c a a s e s a r e x p e c e o r n a n • – i i i f U S 2 0 1 2 t t t |
Agenda
- · Highlights 2011
- Action Plan 2016 Innovation Efficiency
- Operational & Financial Performance 2011
- Growth Outlook
Strong growth and profitability and in d clear investment strategy drive nnovation
Key financials FY 2011: Co ondensed profit & loss statement (IFRS)
| 2 0 0 9 A l t c a u |
2 0 1 0 A l t c a u |
2 0 1 1 A l t c a u |
% s v A l 1 0 t c a u |
||
|---|---|---|---|---|---|
| R e v e n u e s |
4 2 7 |
3 5 5 |
8 0 1 |
% 4 5 + |
|
| G i r o s s m a r g n |
4 3 2 % |
4 4 1 % |
% 4 3 7 |
||
| R & D e x p e n s e s • |
2 0 9 |
6 1 |
8 4 |
3 8 % + |
S t i r o n g o r g a n c |
| S G & A e p e n s e s x • |
1 6 7 |
1 6 0 |
1 8 5 |
1 % - |
t h g r o w t m o m e n u m |
| A i i t t m o r s a o n • |
0 5 |
0 7 |
1 7 |
- r e v e n u e s |
|
| I i t m p a r m e n • |
1 8 2 |
0 0 |
2 1 |
l d i e x c u n g |
|
| f R l i i t e v e r s a o m p a r m e n • |
( ) . 0 4 |
0 0. |
( ( ) ) 1 1 5 5 |
i i t i a c q u s o n s |
|
| R i t t e s r u c u r n g e x p e n s e s • |
4 8 |
0 0 |
0 0 |
% 3 0 + |
|
| O h i t t e r o p e r a n g e p e n s e s x • |
( ) 0 1 |
( ) 0 1 |
3 3 |
||
| O i i ( l ) t p e r a n g n c o m e o s s |
( 4 2 3 ) |
1 7 + |
5 2 + |
2 0 4 % + |
|
| N t i ( l ) e n c o m e o s s |
( 4 5 5 ) |
3 0 + |
6 7 + |
1 2 3 % + |
Growth driven by upfront payments and milestones
Milestones & gross margin n
Significantly impro oved profitability
Operating and net result
Strongp g o erating c infrastructure upg cash flow invested in rade and strategic acquisitions
Cash development in 2011 1
Visit the Manfred EEigen Campus in Hamburg
Significant upgrading proc cesses at all sites
Sales representation (Boston, Tokyo) Operations & sales representation
1) Manfred Eigen (*1927), German biophysical chemist and work on a special measuring method of fast chemical react d one of the worldwide leading pioneers in biotechnology. In 1967, he won the Nobel Prize in Chemistry for his ions, which, until then, were considered to be immeasurable. He initiated the foundation of Evotec AG.
Clear investment ffocus and good cost control
Overview R&D spend & SG G&A
Acquired technolo balance sheetogies and research reflected on
Balance sheet overview
Revenue momentuum maintained in Q4
Q4 2011 results
| Q 4 2 0 1 0 A l t c a u |
Q Q 4 2 0 1 1 A A l t c a u |
% s v A l 1 0 t c a u |
||
|---|---|---|---|---|
| R e e n e s v u |
1 6 4 |
2 0 4 |
2 4 % + |
€ 2 1 i i t m m p a r m e n • |
| G i r o s s m a r g n |
4 4 %. 2 |
3 3 3 0 0 0 0 % % |
f 2 0 1 E V T o |
|
| R & D e x p e n s e s • |
1 9 |
1 7 |
1 5 % - |
M i d i t a r g n r e u c o n • |
| S G & A e x p e n s e s • |
4 4 |
4 3 |
2 % - |
d h i f t e o p a s n g o u i l t m e s o n e s |
| A i i t t m o r s a o n • |
0 4 |
0 5 |
f f D i t e r e n r e v e n u e • |
|
| I i t m p a r m e n • |
0 0 |
2 1 |
i ( d m x c o m p o u n t |
|
| f R l i i t e v e r s a o m p a r m e n • |
0 0. |
0 0 0 0 |
) m a n a g e m e n I i h t n c r e a s e n o e r • |
|
| R i t t e s r u c u r n g e x p e n s e s • |
0 0 |
0 0 |
t i o p e r a n g |
|
| O h i t t e r o p e r a n g e p e n s e s x • |
0 1 - |
1 9 |
d t e p e n s e s e o x u f t t i i t |
|
| O i i ( l ) t p e r a n g n c o m e o s s |
0 7 + |
4 3 - |
o n e m m e e c o s s o - f M d E i a n r e g e n |
|
| N i ( l ) t e n c o m e o s s |
2 2 + |
2 5 - |
C a m p u s |
Double digit reven financial performa nue growth and further improved ance in 2012 ff
Guidance 2012: Double diigit growth, higher profitability, more innovation
Agenda
- · Highlights 2011
- Action Plan 2016 Innovation Efficiency
- Operational & Financial Performance 2011
- Growth Outlook
Go for 2012!
Shareholder structure, upc coming key events & initiatives 2012
Strong news flow to come
Outlook and next steps for r 2012 ff
Key milestones for 2012
| 1 | |
|---|---|
- • Double digit revenue gro owth 2012 – 2016
- EVT Execute Expansion success of ex xisting alliances
- • Significant long-term dea als with major pharma
2EVT Integrate
- • At l t eas 2 i ifi t 2 significant new wi t t d t h l /di integrated technology/disease alliances
- • Deliver significant and a accelerated preclinical/clinical milestones
- • Show operational synerg gies of recent acquisitions
| 3 | E V T |
I t n n o a e v |
|
|---|---|---|---|
- • At least 1 strategic deal for early assets
- • Even more ven innovation u psides (e g (e.g. Cure X, …)
- • Phase III data in DiaPep development partnership p277 and Phase II b start within product ps
Your contact:
Dr Werner LanthalerChief Executive Officer
+49.(0).40.560 81-242 +49.(0).40.560 81-333 Fax [email protected]