Alkermes plc. — Director's Dealing 2016

Dec 8, 2016

SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: Alkermes plc. (ALKS)
CIK: 0001520262
Period of Report: 2016-12-06

Reporting Person: BIBERSTEIN KATHRYN L (EVP/CAO/CCO Alks Inc; Sec ALKS)

Non-Derivative Transactions

Date	Security	Code	Shares	Price	A/D	Holdings After	Ownership
2016-12-06	Ordinary Shares	M	5000	$14.38	Acquired	43687	Direct
2016-12-06	Ordinary Shares	S	5000	$56.2422	Disposed	38687	Direct
2016-12-07	Ordinary Shares	M	5000	$14.38	Acquired	43687	Direct
2016-12-07	Ordinary Shares	S	4100	$56.499	Disposed	39587	Direct
2016-12-07	Ordinary Shares	S	900	$57.1139	Disposed	38687	Direct
2016-12-08	Ordinary Shares	M	4145	$14.38	Acquired	42832	Direct
2016-12-08	Ordinary Shares	S	4145	$55.4179	Disposed	38687	Direct

Derivative Transactions

Date	Security	Exercise Price	Code	Shares	A/D	Expiration	Underlying	Ownership
2016-12-06	Non Qualified Stock Option (Right to Buy)	$14.38	M	5000	Disposed	2016-12-12	Ordinary Shares (5000)	Direct
2016-12-07	Non Qualified Stock Option (Right to Buy)	$14.38	M	5000	Disposed	2016-12-12	Ordinary Shares (5000)	Direct
2016-12-08	Non Qualified Stock Option (Right to Buy)	$14.38	M	4145	Disposed	2016-12-12	Ordinary Shares (4145)	Direct

Holdings (Non-Derivative)

Security	Shares	Ownership
Ordinary Shares	94000	Indirect

Footnotes

F1: This option exercise was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F2: This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F3: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $55.92 to $56.56. Full information regarding the number of shares sold at each separate price can be furnished to the SEC staff upon request.

F4: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $55.99 to $56.97. Full information regarding the number of shares sold at each separate price can be furnished to the SEC staff upon request.

F5: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $57.00 to $57.29. Full information regarding the number of shares sold at each separate price can be furnished to the SEC staff upon request.

F6: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $55.01 to $55.64. Full information regarding the number of shares sold at each separate price can be furnished to the SEC staff upon request.

F7: Shares held by the Kathryn L. Biberstein 2015 Annuity Trust dated December 11, 2015 (the "2015 GRAT"). The Reporting Person is a trustee and beneficiary of the 2015 GRAT and may be deemed to hold voting and dispositive power with regard to the reported shares held by the 2015 GRAT.

F8: These options are fully vested in accordance with their terms.