Alkermes plc. — Director's Dealing 2016

Dec 16, 2016

SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: Alkermes plc. (ALKS)
CIK: 0001520262
Period of Report: 2016-12-14

Reporting Person: FRATES JAMES M (SVP, Alks Inc; CFO ALKS)

Non-Derivative Transactions

Date	Security	Code	Shares	Price	A/D	Holdings After	Ownership
2016-12-14	Ordinary Shares	M	15000	$14.13	Acquired	127342	Direct
2016-12-14	Ordinary Shares	M	10000	$11.74	Acquired	137342	Direct
2016-12-14	Ordinary Shares	S	24900	$54.7234	Disposed	112442	Direct
2016-12-14	Ordinary Shares	S	100	$55.20	Disposed	112342	Direct

Derivative Transactions

Date	Security	Exercise Price	Code	Shares	A/D	Expiration	Underlying	Ownership
2016-12-14	Employee Stock Option (Right to Buy)	$14.13	M	15000	Disposed	2017-11-05	Ordinary Shares (15000)	Direct
2016-12-14	Employee Stock Option (Right to Buy)	$11.74	M	10000	Disposed	2020-05-17	Ordinary Shares (10000)	Direct

Holdings (Non-Derivative)

Security	Shares	Ownership
Ordinary Shares	4000	Indirect
Ordinary Shares	41041	Indirect
Ordinary Shares	16562	Indirect
Ordinary Shares	11421	Indirect

Footnotes

F1: This option exercise was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F2: This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F3: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $54.20 to $55.19. Full information regarding the number of shares sold at each separate price can be furnished to the SEC staff upon request.

F4: Shares held by James M. Frates Grantor Retained Annuity Trust dated March 14, 2014 (the "GRAT"). The Reporting Person is a trustee and beneficiary of the GRAT and may be deemed to hold voting and dispositive power with regard to the reported shares held by the GRAT.

F5: Shares held by the James M. Frates Grantor Retained Annuity Trust dated May 29, 2015 (the "2015 GRAT"). The Reporting Person is a trustee and beneficiary of the 2015 GRAT and may be deemed to hold voting and dispositive power with regard to the reported shares held by the 2015 GRAT.

F6: Shares held by the James M. Frates Grantor Retained Annuity Trust No. 2 dated November 25, 2015 (the "2015 GRAT No. 2"). The Reporting Person is a trustee and beneficiary of the 2015 GRAT No. 2 and may be deemed to hold voting and dispositive power with regard to the reported shares held by the 2015 GRAT No. 2.

F7: These options are fully vested in accordance with their terms.